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Also shown are the adverse clinical outcomes associated with elevated systemic TMAO levels in subjects, and enhanced cardiometabolic phenotypes observed with elevated TMAO levels in animal models (46, 12, 13, 1618)

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* Reference intake for an average adult (8400 kJ/2000 kcal)

The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

Regular blood tests may be necessary to evaluate nutrient levels, assess for toxicity, and track overall health status