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132, 139 Mitochondrial histology and ultrastructural abnormalities in children with ASD/MD One case series reported several mitochondrial histological abnormalities, including variations in muscle fiber size, regenerating fibers, atrophic fibers, muscle inflammation, increased myofiber lipid content and reduced cytochrome oxidase staining

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Pyruvate is metabolized to lactate and alanine, leading to elevations in these metabolites when pyruvate metabolism is impaired

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Therefore, the most promising saponin combination therapies to date appear to be those that achieve mechanistic complementarity by targeting the weaknesses of chemotherapeutic agents

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Energy expenditure at rest and during exercise in nonobese female cyclical dieters and in nondieting control subjects

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Nezu, J

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