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Primary Medical Use Weight Management: For adults with an initial body mass index (BMI) of 30 kg/m or greater (obesity), or 27 kg/m or greater (overweight) in the presence of other risk factors such as type 2 diabetes, dyslipidemia, or controlled hypertension

Bock J, Covassin N, Somers V

[DOI] [PubMed] [Google Scholar] 34.Barker BF, Carpenter WM, Daniels TE, Kahn MA, Leider AS, Lozada-Nur F

May 6, 2022

MICC is typically IM , though standalone B12 is approved for SubQ or IM routes

Beyond subjective pain relief, the trials also measured objective neurological improvements using the Neuropathy Impairment Score (NIS), which evaluates muscle weakness, reflex loss, and sensation loss