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[59] Agents associated with a moderately increased risk include nonsteroidal anti-inflammatory drugs (such as ibuprofen), bisphosphonates, and other chemotherapeutic agents such as melphalan, interleukin-2, and anthracyclines

Contributing Factors Several factors can exacerbate acne or make it more difficult to manage: Diet High-glycemic foods, dairy products, and diets rich in processed sugars can trigger or worsen acne

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It can cause pneumonia, decreased vital capacity, and shortening of the intercostal muscles and fascia for many years

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