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Because the attractions between the particles are so similar, the freedom of movement of the ethanol molecules in the water solution is about the same as their freedom of movement in the pure ethanol

Available from: Le Merdy M, Spires J, Tan ML, Zhao L, Lukacova V (2024) Clinical ocular exposure extrapolation for a complex ophthalmic suspension using physiologically based Pharmacokinetic modeling and simulation

doi: 10.1038/s41573-021-00139-y

Mol Cancer Ther 6:31583168

It also explains why the same person might be dosed differently at two points in time: as tolerance, response, and objectives shift, so can the appropriate amount

Today, RCTs remain the gold standardbut they are not without critics