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Therefore, the association of non-radical ROS with disease is fundamentally dose- and context-dependent, positioning them as critical but double-edged players in cellular homeostasis and pathogenesis

Photoaging typically manifests as dryness, roughness, deepening wrinkles, skin laxity, vascular changes, and hyperpigmentation in sun-exposed areas (Zouboulis and Hoenig, 2019)

M., & Hazen, S

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So, there is no one-size-fits-all answer