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Following are several examples of how FDA has addressed expiry dating challenges following PAHPRAs enactment and before PAHPRA: COVID-19 Vaccines Vaccines authorized for emergency use as products that are not approved under a biologics license application and are still being studied under investigational new drug applications do not have fixed expiry dates

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Patient non-compliance with paper diaries

[11] A Tobacco Control study using sales data through 2023 reported that per-capita and total cigarette sales in Japan declined by 52.6% and 52.7%, respectively, between 2011 and 2023

Document inconsistencies Differences between shipping documents and physical goods may trigger customs inspection

"Smoking ban information website"