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These insights lay the foundation for developing novel therapies targeting energy metabolism in neurodegenerative and metabolic brain conditions, with further preclinical studies planned to assess safety and efficacy

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GLS1 inhibitors, such as BPTES, reduce ATP production through glutamate deficiency, and finally inhibit cancer cell growth (86)

Crit Rev Toxicol 44(3):270297

Diabetes, oxidative stress, nitric oxide and mitochondria function