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These symptoms arise from the abrupt loss of the sedative and muscle relaxant effects of benzodiazepines, leading to central nervous system hyperexcitability

Chronic stress, cortisol dysfunction, and pain: a psychoneuroendocrine rationale for stress management in pain rehabilitation

McGarrity S, Anuforo O, Halldorsson H, Bergmann A, Halldorsson S, Palsson S, Henriksen HH, Johansson PI, Rolfsson O (2018) Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification

It also brought the SOD, catalase, GPx, and GSH levels to normal and decreased lipid peroxidation in the kidney and liver of streptozotocin-induced diabetic rats