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(ii) CMS designates an alternative quality performance standard for an ACO that does not meet the criteria described in paragraph (a)(2) or (a)(5)(i) of this section as the following: (A) For performance year 2024, the ACO reports quality data on the APP quality measure set established under 414.1367 of this subchapter according to the method of submission established by CMS and achieves a quality performance score equivalent to or higher than the 10th percentile of the performance benchmark on at least one of the four outcome measures in the APP quality measure set

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Animal work has shown effects on gastric ulcer healing, intestinal anastomosis, and inflammatory bowel models [Drmic et al., World Journal of Gastroenterology, 2017]

Clinical data shows low incidence rates

Badia J, Pascual-Font A, Viv M, Udina E, Navarro X (2010) Topographical distribution of motor fascicles in the sciatic-tibial nerve of the rat

Although NAC is promising as a supplement to both boost glutathione levels and potentially mitigate some of the issues related to oxidative stress, the research is not conclusive, and some of the findings are disease-specific