Furthermore, intracellular iron overload can be induced by certain exogenous substances that contain iron (such as heme chloride, FeCl 2 , and (NH 4 ) 2 Fe(SO 4 ) 2 ), leading to the effective initiation of ferroptosis
2002;282:H1255-H1261
Higher levels of glucose observed in T1 as compared to that in T2 could be attributed to the fast metabolism of available glucose to cope with high energy needs
GBM cells exhibit dysregulated iron metabolism (transferrin receptor overexpression, impaired iron efflux) and altered lipid metabolism (changes in desaturase activity, membrane phospholipid remodeling), conferring heightened ferroptosis susceptibility compared to normal neural cells [10]
After 6 hours of incubation in 50 g/ml GO, we detected increased numbers of both autophagosomes and light spots
Meals may feel more filling and cravings may decrease