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Following acute brain injury, HPA axis activation by inflammatory mediators such as IL-6 triggers a systemic compensatory anti-inflammatory response to protect peripheral organ function

By the time a standard pill passes through your digestive tract, much of the glutathione may be lost

Pharmacogenomics 16(8):891903 Stocco G, Pelin M, Franca R, De Iudicibus S, Cuzzoni E, Favretto D et al (2014) Pharmacogenetics of azathioprine in inflammatory bowel disease: a role for glutathione-S-transferase