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10.1105/tpc.12.10.1939 35 MontezanoA

A Therapeutic Use Exemption (TUE) allows a WADA-tested athlete to use a prohibited substance for a legitimate medical need

One mechanism that contributes to cytochrome c detachment from IMM involves cardiolipin oxidation because oxidized cardiolipin has a much lower affinity for cytochrome c than the reduced form

In summary, this study demonstrates that calcium overload plays a critical role in the cytotoxicity associated with a-synucleinopathy, leading to mitochondrial damage, lysosomal dysfunction, and cell death

& Swartz, M