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Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense

Participants with liver fat content between 2.5-5% had an adjusted HR 1.02 (0.54-1.93), between 5-10% 1.86 (1.04-3.31), for 10-15% 1.89 (0.96-3.72), for 15-20% 1.98 (0.96-4.05), for 20-25% 2.27 (1.04-4.98), for 25-30% 2.44 (0.93-6.44)), and for those with liver fat content of 30% or more it was 3.23 (1.57-6.63) for the occurrence of CMD, compared to those with a liver fat content between 0 and 2.5%

However, the precise control of ferroptosis, including its induction, inhibition, and fine-tuning, remains an area of ongoing scientific discourse (128)