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6.1.3 Iron chelators Deferiprone (DFP), an FDA-approved oral iron chelator capable of crossing the bloodbrain barrier, reduces nigral iron content, suppresses -syn aggregation, and protects DA neurons through dual inhibition of iron-dependent -syn fibrillation and ferroptosis

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Progress in understanding the molecular signatures involved in the redox regulations that link central metabolism and stress pathways will help to define novel strategies for optimal fruit production and storage ( Funding The authors are also grateful to the MetaboHUB (ANR-11-INBS-0010) and PHENOME (ANR-11-INBS-0012) projects for financial support

AOR: adjusted odds ratio