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The APP(V642I) KI mouse model was engineered by introducing the V717I mutation into exon 17 of the mouse APP gene using homologous recombination and the Cre-loxP system

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Journal of Clinical Neuroscience 19(8):1159-1164

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Long-term effects of hypophysectomy on various fractions of sulfhydryl groups in thyroid, adrenal, and some other organs in the rat