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J Cell Physiol 234:24472459

In JC virus-infected glioblastoma cells, it is possible to find the same MDR feature

The products generated in this reaction are peroxynitrite (ONOO ) which results from the formation of hydroxyl radical (OH), which is greatly reactive and results in the alteration of cellular functioning and cause dysfunction of endothelial cells, and 3) Massive generation of O 2 may result in proliferation and apoptotic death of epithelial cells (Pacher et al., 2007

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This may be because its effects depend on a number of factors such as the redox state of the body, the dose used, and also on the tissue metabolism

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