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A study by Banerjee et al (172) revealed that the A-mini-chaperone binds to Phe56, Val132, and Val164 to Leu167 of D-crystallin to protect it from aggregation and oxidation

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The membrane-bound folate receptor has the highest affinity for folate (Kd 0.11 nmol/l), characteristically binds folic acid, reduced folates, many antifolate drugs, and folate conjugates, and transports them by a non-classical endocytic mechanism 881,885