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Expectedly, depletion of cystine or inhibition of the Xc- antiporter using synthetic small molecule inhibitors including erastin, sulfasalazine, sorafenib and even excess of glutamate triggered cystine depletion, decreased GSH level and reduced GPX4 activity, culminating in ferroptosis induction

[PubMed] [Google Scholar] 120.Sjquist B., Stjernschantz J

Stewart DJ, Nunez MI, Behrens C, Liu D, Lin YH, Lee JJ, Roth J, Heymach J, Swisher SG , Hong WK, Wistuba II

We mention this condition to highlight the connection between PCOS and liver detoxification

Frontiers in Immunology, 10

However, it lacks the direct GHRH receptor activation that sermorelin provides