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When viewed in this context, it led us to ask whether parkin-dependent, redox-based mechanisms could explain heretofore unresolved findings from unbiased, proteomic-based investigations of parkin-deficient mice

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3.1.2 Roles of ROS in the pathophysiology of other diseases 3.1.2.1 Liver diseases The liver is the second largest organ in the organisms body

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Unaltered levels of glutathione status in lung tissue of ApoE -/- mice after pulmonary exposure to CB and/or LPS As a measure of oxidative stress, total and reduced glutathione were measured in lung homogenate 24 h after last exposure (Fig 3)

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