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Overall, experience from the oncology field suggests that amino acid metabolism intervention is more likely to be implemented through well-defined clinical development strategies, including monotherapy or combination therapy, dose escalation, safety monitoring, and immune pharmacodynamic endpoints, and may provide a useful framework for trial design and stratification in immune-mediated diseases

doi: 10.5530/jyp.2023.15.59 8

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A stalled methylation cycle also starves the downstream transsulfuration pathway, which is responsible for synthesizing glutathione

One clinical study examined the impact of SS-31 on patients with primary mitochondrial myopathies, a group of disorders that affect muscle function due to mitochondrial dysfunction

These effects are usually mild and improve as your scalp adjusts