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In psoriasis, T cells together with their cytokines and chemokines are shown to induce serious inflammation by Th1- and Th17-driven immune response including IL-20, IL-23, IL-12, IL-17 and IL-22 [2, 3, 4, 5]

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Therefore, further research on these compounds, including their isolation, structural elucidation, and characterization, is needed to evaluate their efficacy and safety

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The protein level of significantly increased p16 was confirmed in keloid lesions and fibroblasts based on western blot analysis ( p = 0.0007, p = 0.03

Moreover, it has been shown that chronic ammonium exposure in cultures of the granule neurons of the cerebellum induces the redistribution of protein kinase C (PKC) isoforms in the membrane and cytosol, thus causing cell dysfunction (Giordano et al., 2005)